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于君教授

來源：泰然健康網(wǎng) 時(shí)間：2025年04月03日 19:07

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于君教授

助理院長 (內(nèi)地事務(wù))

卓敏內(nèi)科及藥物治療學(xué)講座教授

中大職務(wù)

醫(yī)學(xué)院助理院長 (內(nèi)地事務(wù))

卓敏內(nèi)科及藥物治療學(xué)講座教授

內(nèi)科及藥物治療學(xué)系教授

消化疾病研究所主任

消化疾病研究實(shí)驗(yàn)室主任

消化疾病研究國家重點(diǎn)實(shí)驗(yàn)室主任

專業(yè)範(fàn)疇胃腸道腫瘤發(fā)生機(jī)制脂肪性肝病腸道微生態(tài)和腫瘤教育及資歷

MB, MM (Heibei Med); MD, PhD (Tongji Med).

專注研究消化道腫瘤發(fā)生過程中的基因組和表觀遺傳學(xué)組異常改變腸道微生態(tài)，細(xì)菌和宿主細(xì)胞的相互作用和腫瘤的發(fā)生和發(fā)展非酒精性脂肪肝病和其相關(guān)肝癌的發(fā)病機(jī)制和治療靶點(diǎn)消化道腫瘤診斷和治療標(biāo)誌物更多資訊

獎(jiǎng)項(xiàng)及榮譽(yù)

第七屆中國女醫(yī)師協(xié)會(huì)五洲女子科技獎(jiǎng)基礎(chǔ)醫(yī)學(xué)科研創(chuàng)新獎(jiǎng), 2021國家自然科學(xué)獎(jiǎng)二等獎(jiǎng), 2020何梁何利基金科學(xué)與技術(shù)進(jìn)步獎(jiǎng), 2018美國胃腸病學(xué)會(huì)腫瘤研究導(dǎo)師獎(jiǎng), 2017藥明康得生命化學(xué)研究獎(jiǎng), 2017國家自然科學(xué)獎(jiǎng)二等獎(jiǎng), 2016國家創(chuàng)新團(tuán)隊(duì)獎(jiǎng), 2016香港裘槎卓越科研獎(jiǎng)等, 2016香港中文大學(xué)醫(yī)學(xué)院傑出研究員, 2015教育部自然科學(xué)獎(jiǎng)一等獎(jiǎng), 2014 & 2010國家科技進(jìn)步獎(jiǎng)二等獎(jiǎng), 2012教育部科技進(jìn)步獎(jiǎng)一等獎(jiǎng), 2012

專業(yè)服務(wù)

中國抗癌協(xié)會(huì)微生態(tài)與腫瘤學(xué)會(huì)副主任美國胃腸病學(xué)會(huì)微生態(tài)和代謝常務(wù)理事國際腫瘤微生態(tài)學(xué)會(huì)（英國）理事

美國胃腸病學(xué)會(huì)腫瘤常務(wù)理事

教育部長江學(xué)者講座教授

香港科學(xué)家協(xié)會(huì)副主席

Oncogene 副編輯； Gut、Scientific Reports 及 JGH 編輯

香港免疫學(xué)會(huì)主席, 2017-2018

香港流式細(xì)胞學(xué)會(huì)主席, 2015-2016

部分論文 (只有英文版本)Zhang X, Fan L, Wu J, Xu H, Leung WY, Fu K, Wu J, Liu K, Kwan M, Yang X, Han J, Ren J, Yu J. Macrophage p38α promotes nutritional steatohepatitis through M1 polarization. J Hepatol. 2019 Jul;71(1):163-174. Coker OO, Nakatsu G, Dai RZ, Wu WKK, Wong SH, Ng SC, Chan FKL, Sung JJY, Yu J. Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer. Gut. 2019 Apr;68(4):654-662. Liang JQ, Teoh N, Xu L, Pok S, Li X, Chu ESH, Chiu J, Dong L, Arfianti E, Haigh WG, Yeh MM, Ioannou GN, Sung JJY, Farrell G, Yu J. Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling. Nat Commun. 2018 Oct 26;9(1):4490. Nakatsu G, Zhou H, Wu WKK, Wong SH, Coker OO, Dai Z, Li X, Szeto CH, Sugimura N, Yuen-Tung Lam T, Chi-Shing Yu A, Wang X, Chen Z, Chi-Sang Wong M, Ng SC, Chan MTV, Chan PKS, Leung Chan FK, Jao-Yiu Sung J, Yu J. Alterations in Enteric Virome Associate With Colorectal Cancer and Survival Outcomes. Gastroenterology. 2018 Aug;155(2):529-541.e5. Coker OO, Dai Z, Nie Y, Zhao G, Cao L, Nakatsu G, Wu WK, Wong SH, Chen Z, Sung JJY, Yu J. Mucosal microbiome dysbiosis in gastric carcinogenesis. Gut. 2018 Jun;67(6):1024-1032. Sun W, Zhang Y, Wong KC, Liu K, Yang Y, Wu B, Tong JH, Chan AW, Chan HL, Yu J. Increased expression of GATA Zinc Finger Domain Containing 1 via gene amplification promotes liver cancer by directly inducing PRL3. Hepatology. 2018 Jun;67(6):2302-2319.Liu D, Wong CC, Fu L, Chen H, Zhao L, Li C, Zhou Y, Zhang Y, Xu W, Yang Y, Wu B, Cheng G, Lai PB, Wong N, Sung JJY, Yu J. Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target. Sci Transl Med. 2018 Apr 18;10(437). Tsoi H, Chu ES, Zhang X, Sheng J, Nakatsu D, Ng SC, Chan AW, Chan FK, Sung JJ, Yu J. Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice. Gastroenterology. 2017 May;152(6):1419-1433.e5. Wong CC, Qian Y, Li X, Xu J, Kang W, Tong JH, To KF, Jin Y, Li W, Chen H, Go MY, Wu JL, Cheng KW, Ng SS, Sung JJ, Cai Z, Yu J. SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations, and Xenograft Tumor Progression in Mice, via Intracellular Synthesis of Aspartate. Gastroenterology. 2016 Nov;151(5):945-960. Zhang J, Tsoi H, Li X, Wang H, Gao J, Wang K, Go MY, Ng SC, Chan FK, Sung JJ, Yu J. Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP-WT1-TBL1 axis. Gut. 2016 Sep;65(9):1482-93.

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