Background and Objectives: Oral disorders, frequently observed in patients with primary Sj?gren's syndrome, can profoundly affect patients' daily lives and well-being, as oral health represents a fundamental part of general health. Saliva plays an essential part in maintaining and protecting oral health, so the decrease in its quantity and quality leads to chronic oral discomfort alongside a broad spectrum of problems. The objective of the present study was to evaluate the oral health of patients with primary Sj?gren's syndrome and establish its effect on the different domains of their oral health-related quality of life (OHRQoL). Materials and Methods: The research was designed as an observational case-control study with prospective data collection. Eighty patients, divided into two groups based on their oral status, participated in the study. All subjects underwent a complete oral examination. The OHRQoL was assessed using the Oral Health Impact Profile-14 (OHIP-14). Results: The most prevalent oral manifestation was exfoliative cheilitis, while 30% of subjects complained of chewing and swallowing difficulties. The OHIP-14 summary score was significantly higher in the patients with oral lesions (26.0 (5.0) vs. 17.0 (4.0), respectively; p < 0.001). Oral manifestations, systemic involvement, medication, and periodontal indexes were significantly associated with OHIP-14 scores. Conclusions: Patients with oral alterations had a substantially decreased OHRQoL. These findings emphasize the importance of oral diseases for patients' well-being. Therefore, it is essential for dentists to be included in the multidisciplinary teams managing primary Sj?gren's syndrome, as improving patients' oral status would lead to better oral health and enhanced OHRQoL.

中文翻譯：

原發(fā)性干燥綜合征患者的口腔健康和口腔健康相關(guān)生活質(zhì)量。

背景和目的：在原發(fā)性干燥綜合征患者中經(jīng)常觀察到的口腔疾病會(huì)深刻影響患者的日常生活和健康，因?yàn)榭谇唤】凳侨斫】档幕窘M成部分。唾液在維持和保護(hù)口腔健康方面起著重要作用，因此其數(shù)量和質(zhì)量的下降會(huì)導(dǎo)致慢性口腔不適以及一系列廣泛的問題。本研究的目的是評(píng)估原發(fā)性干燥綜合征患者的口腔健康狀況，并確定其對(duì)口腔健康相關(guān)生活質(zhì)量 (OHRQoL) 不同領(lǐng)域的影響。材料和方法：該研究被設(shè)計(jì)為具有前瞻性數(shù)據(jù)收集的觀察性病例對(duì)照研究。八十名患者，根據(jù)口腔狀況分為兩組，參與了這項(xiàng)研究。所有受試者都接受了完整的口試。使用 Oral Health Impact Profile-14 (OHIP-14) 評(píng)估 OHRQoL。結(jié)果：最普遍的口腔表現(xiàn)是剝脫性唇炎，而 30% 的受試者抱怨咀嚼和吞咽困難?？谇徊∽兓颊叩?OHIP-14 總分明顯更高（分別為 26.0 (5.0) 和 17.0 (4.0)；p < 0.001）?？谇槐憩F(xiàn)、全身受累、藥物治療和牙周指數(shù)與 OHIP-14 評(píng)分顯著相關(guān)。結(jié)論：口腔改變患者的 OHRQoL 顯著降低。這些發(fā)現(xiàn)強(qiáng)調(diào)了口腔疾病對(duì)患者健康的重要性。因此，牙醫(yī)必須參與管理初級(jí)干燥綜合征的多學(xué)科團(tuán)隊(duì)

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