ZHAO Can, GAO Shenghua, ZHANG Lan. Investigation on the Method of Deriving Health Risk Advisory Value for Acute Exposure to Contaminants in Drinking Water in China[J]. Journal of Environmental Hygiene, 2018, 8(1): 7-11. DOI: 10.13421/j.cnki.hjwsxzz.2018.01.002

Citation: ZHAO Can, GAO Shenghua, ZHANG Lan. Investigation on the Method of Deriving Health Risk Advisory Value for Acute Exposure to Contaminants in Drinking Water in China[J]. Journal of Environmental Hygiene, 2018, 8(1): 7-11. DOI: 10.13421/j.cnki.hjwsxzz.2018.01.002

我國飲用水中污染物短期暴露健康風險參考值推導方法研究

中國疾病預防控制中心環(huán)境與健康相關產(chǎn)品安全所

詳細信息

作者簡介:

趙燦, 主要從事飲水安全與健康研究

通訊作者:

張嵐, 研究員, 從事水質(zhì)安全監(jiān)測研究; Email:676360708@qq.com

聯(lián)系方式： 北京市西城區(qū)南緯路29號；郵編:100050; Email: zcan0111@163.com

中圖分類號: R123

計量 文章訪問數(shù):  0 HTML全文瀏覽量:  0 PDF下載量:  0 出版歷程 網(wǎng)絡出版日期:  2023-06-24 發(fā)布日期:  2018-02-24 刊出日期:  2018-02-24

Investigation on the Method of Deriving Health Risk Advisory Value for Acute Exposure to Contaminants in Drinking Water in China

摘要

目的

近年來我國接連發(fā)生的自來水停水事件嚴重影響城市供水安全，給公眾生活和社會秩序帶來了很大困擾。鑒于《生活飲用水衛(wèi)生標準》（GB 5749-2006）中污染物限值確定的依據(jù)是基于終生暴露水平的健康風險評價，與污染事件應急處置中常見的污染物短期暴露風險的評價角度不同，從而開展我國飲用水中污染物短期暴露健康風險的研究，確定健康風險參考值的推導方法。

方法

飲用水短期暴露健康風險參考值制定的主要步驟包括毒理數(shù)據(jù)的收集和篩選、分離點的確定、不確定系數(shù)的選擇和推導健康風險參考值。

結(jié)果

飲用水污染物短期暴露健康風險參考值的推導公式為${rm{HA}} = frac{{{rm{POD}} times {rm{BW}}}}{{{rm{UF}} times {rm{DWI}}}}$。

結(jié)論

本研究提出了飲用水中污染物短期暴露健康風險參考值的制定方法，為完善我國飲用水中污染物健康風險評價體系和污染物的短期健康風險評估與飲用水污染事件應急處置工作提供了技術支持。

Objectives

The occurrence of tap-water shutdown event, which was frequent in recent years in China, had serious impact on the safety of water supply, and had great trouble to public life and social order. In light of the limiting value of pollutants in the Standards for Drinking Water Quality(GB 5749-2006)was based on the assessment of health risk exposure to contaminants in drinking water in the lifetime, the point of view on assessing the health risk of acute exposure to contaminants in drinking water during emergent events was different. Thus, a research on the method of deriving a advisory value for the health risk of acute exposure to contaminants in drinking water was carried out.

Methods

Main steps of deriving advisory values for health risk in acute exposure to contaminants in drinking water included collection and selection of toxicological data, determination of departure points, selection of uncertainty factors and derivation of health risk advisory value.

Results

The health risk advisory value of acute exposure to contaminants in drinking water was derived from the following equation ${rm{HA}} = frac{{{rm{POD}} times {rm{BW}}}}{{{rm{UF}} times {rm{DWI}}}}$.

Conclusions

The method of deriving health risk advisory values for acute exposure to contaminants in drinking water was put forward in this study, which provided technical support in improving health risk assessment system for assessing health risk and emergent treatment of drinking water pollution events in China.

HTML全文

圖  1   我國近5年來發(fā)生的部分飲用水污染事件

圖  2   短期暴露健康風險參考值制定主要步驟

參考文獻(13)

[1] 吉立, 劉晶, 李志威, 等.2011-2015年我國水污染事件及原因分析[J].生態(tài)與農(nóng)村環(huán)境學報, 2017, 33(9):775-782. doi: 10.11934/j.issn.1673-4831.2017.09.002

Ji L, Liu J, Li ZW, et al. Accidents of water pollution in China in 2011-2015 and their causes[J]. J Ecol Rural Environ, 2017, 33(9):775-782. doi: 10.11934/j.issn.1673-4831.2017.09.002

[2] 張曉健, 林朋飛, 陳超.江西新余仙女湖鎘鉈砷突發(fā)環(huán)境事件應急供水[J].中國給水排水, 2017, 33(9):1-10. http://www.doc88.com/p-9817833675994.html [3] 李莎莎. 環(huán)保部通報嘉陵江(廣元段)鉈污染事件處置情況[EB/OL]. (2017-07-18). [2018-3-06]. http://www.sc.gov.cn/10462/12771/2017/7/18/10428354.shtml. [4] 中華人民共和國衛(wèi)生部, 中國國家標準化委員會. GB 5749-2006生活飲用水衛(wèi)生標準[S]. 北京: 中國標準出版社, 2007.

Ministry of Health of the People's Republic of China, Standardization Administration of the People's Republic of China. GB 5749-2006 Standards for drinking water quality[S]. Beijing:Standards Press of China, 2007.

[5]

World Health Organization. Guidelines for Drinking water Quality[M].4th edition, 2011.

[6]

USEPA. 2012 Edition of the Drinking Water Standards and Health Advisories[EB/OL].(2012-04-01).[2017-12-01]. https://nepis.epa.gov/Exe/ZyPDF.cgi/P100N01H.PDF?Dockey=P100N01H.PDF.

[7]

USEPA. Integrated Risk Information System[EB/OL].(2018-02-01).[2018-2-08]. http://www.epa.gov/iris.

[8]

USEPA. Benchmark Dose Tools[EB/OL].(2017-08-18).[2018-1-20]. http://www.epa.gov/NCEA/bmds/.

[9]

RIVM. Proast[EB/OL].(2011-04-08).[2017-11-20]. http://www.rivm.Nl/proast.

[10]

Donohue JM, Lipscomb JC. Health advisory values for drinking water contaminants and the methodology for determining acute exposure values[J]. Sci Total Environ, 2002, 288(1-2):43-49. doi: 10.1016/S0048-9697(01)01109-3

[11] 李文婷, 宋超, 呂釗, 等.西維因環(huán)境內(nèi)分泌干擾效應的非受體介導作用機制研究進展[J].生態(tài)學雜志, 2013, 32(12):3385-3391. http://edu.wanfangdata.com.cn/Periodical/Detail/stxzz201312038

Li WT, Song C, Lü Z, et al. Non-receptor-mediated action mechanisms of endocrine disrupt effect in carbaryl environment[J]. Chin J Ecol, 2013, 32(12):3385-3391. http://edu.wanfangdata.com.cn/Periodical/Detail/stxzz201312038

[12]

Carpenter CP, Weil CS, Palm PE, et al. Insecticide Toxicology, mammalian toxicity of 1-naphthyl-N-methylcarbamate (Sevin insecticide)[J]. J Agric Food Chem, 1961, 9(1):30-39. doi: 10.1021/jf60113a009

[13]

Weil CM, Woods W, Bernard J, et al. Sevin:results of feeding in the diet of rats for one week & for one week plus one day on control diets[R]. MRID 00118393, 1968.

施引文獻

資源附件(0)

圖(2)

計量 文章訪問數(shù):  0 HTML全文瀏覽量:  0 PDF下載量:  0 出版歷程 網(wǎng)絡出版日期:  2023-06-24 發(fā)布日期:  2018-02-24 刊出日期:  2018-02-24

目錄

相關知識

環(huán)境污染物聯(lián)合暴露的人體健康累積風險評估研究進展
地下水砷污染健康風險評估研究
地下水污染健康風險評價
孕期環(huán)境危險因素暴露的健康效應研究
長江鎮(zhèn)江段苯酚污染事件殘留物健康風險評估研究
大氣化學團隊聯(lián)合研究提出基于氣溶膠人群暴露健康風險的污染防控機制
典型污染物的環(huán)境暴露與健康危害機制
污染場地健康風險評價方法
地下水污染健康風險評估工作指南（試行） .pdf
復旦研究：連續(xù)5年霸榜的空氣污染物，顯著升高中國孕婦的高血壓風險！這段時期最危險...

網(wǎng)址: 我國飲用水中污染物短期暴露健康風險參考值推導方法研究 http://www.u1s5d6.cn/newsview428035.html