首頁資訊特邀講座——用于無創(chuàng)個(gè)人健康監(jiān)測(cè)的實(shí)用可穿戴電子平臺(tái)

特邀講座——用于無創(chuàng)個(gè)人健康監(jiān)測(cè)的實(shí)用可穿戴電子平臺(tái)

來源：泰然健康網(wǎng) 時(shí)間：2024年12月21日 15:54

講座簡(jiǎn)介：

用于非侵入式個(gè)人健康監(jiān)測(cè)的實(shí)用可穿戴電子平臺(tái)需要先進(jìn)的傳感模式和高度集成的電子系統(tǒng)。然而，由于能量供應(yīng)不足、傳感系統(tǒng)能力有限、用戶體驗(yàn)問題、復(fù)雜的電路調(diào)節(jié)以及設(shè)備尺寸較大，這些系統(tǒng)在長(zhǎng)期連續(xù)健康監(jiān)測(cè)方面面臨諸多限制。通過應(yīng)用可穿戴微電網(wǎng)設(shè)計(jì)理念，我們提出了一種可穿戴、無線、能量自主的多路汗液檢測(cè)系統(tǒng)，該系統(tǒng)可在指尖上運(yùn)行。該系統(tǒng)利用高效、自我電壓調(diào)節(jié)的可穿戴微電網(wǎng)，由酶生物燃料電池（BFCs）和氯化銀-鋅（AgCl-Zn）電池組成，從自然出汗中獲取并儲(chǔ)存能量，無需任何身體運(yùn)動(dòng)或體力消耗。關(guān)鍵的設(shè)計(jì)考量包括精準(zhǔn)的能量預(yù)算、兼容的電路調(diào)節(jié)以及針對(duì)特定場(chǎng)景的互補(bǔ)特性，這些都被用于無縫創(chuàng)建能量微電網(wǎng)，并將其與傳感器陣列和微控制器集成至單個(gè)指尖。該傳感模式結(jié)合了滲透泵和紙基流體系統(tǒng)，能夠持續(xù)將指尖自然汗液輸送到傳感器陣列，以實(shí)現(xiàn)按需的多代謝物檢測(cè)。通過低功耗電子設(shè)備進(jìn)行信號(hào)采集和無線數(shù)據(jù)傳輸，該系統(tǒng)可以完全依靠自然指尖汗液供電，持續(xù)檢測(cè)葡萄糖、抗壞血酸、乳酸和左旋多巴水平。這種集成在指尖的汗液監(jiān)測(cè)系統(tǒng)為輕松、可靠、且自我可持續(xù)的綜合非侵入式代謝監(jiān)測(cè)提供了一種解決方案。

主講人：丁士超

主講人簡(jiǎn)介：

丁士超博士目前是加州大學(xué)圣地亞哥分校（UCSD）納米工程系的博士后學(xué)者，與著名教授Joseph Wang合作。他于2022年在華盛頓州立大學(xué)（WSU）獲得博士學(xué)位，導(dǎo)師為林岳和教授。他的研究領(lǐng)域主要集中在基于功能性納米材料（特別是單原子催化劑和類酶）的電催化和類酶催化、生物傳感以及可穿戴電子設(shè)備和微電網(wǎng)等方面。截至目前，丁博士已發(fā)表78篇學(xué)術(shù)論文，其中34篇為第一作者、共同第一作者或通訊作者。這些論文發(fā)表在《Nature Medicine》、《Nature Electronics》、《Nature Reviews Materials》、《Nature Reviews Endocrinology》、《Advanced Materials》、《Advanced Energy Materials》等國(guó)際頂尖期刊上。他的論文被引用次數(shù)超過3300次，Google Scholar顯示其H指數(shù)為31。此外，丁博士還擔(dān)任多家學(xué)術(shù)期刊的編輯委員會(huì)成員或青年編輯，包括《Bioengineering》、《The Innovation》、《Advanced Powder Materials》、《Exploration》、《VIEW》、《Soft Science》、《Med-X》等。他也是100多種期刊的同行評(píng)審員，包括《Nature Synthesis》、《Nature Communications》等，累計(jì)完成審稿約400次。

講座時(shí)間：11月16日 13:30

講座地點(diǎn)：復(fù)旦大學(xué)江灣校區(qū)教學(xué)樓JA105

Lecture Bio:

Practical wearable electronics platforms for non-invasive personal health monitoring require advanced sensing modalities and highly integrated electronic systems. However, these systems face limitations in long-term continuous healthcare monitoring due to inadequate energy supply, limited sensing system capabilities, user experience issues, complex circuitry regulation, and large device dimensions. By applying the wearable microgrid design concept, we present a wearable, wireless, energy-autonomous, multiplexed sweat sensing system that operates on the fingertip. This system utilizes a high-efficiency, self-voltage-regulated wearable microgrid, composed of enzymatic biofuel cells (BFCs) and silver chloride-zinc (AgCl-Zn) batteries, to harvest and store energy from natural perspiration without requiring any body movement or physical exertion. Critical design considerations, including accurate energy budgeting, compatible circuit regulation, and scenario-specific complementary characteristics, were employed to seamlessly create the energy microgrid and integrate it with the sensor array and microcontroller onto a single fingertip. The sensing modality combines an osmotic pump and paper fluidic system to continuously deliver natural fingertip perspiration to a sensor array for on-demand multi-metabolite sensing. Coupled with low-power electronics for signal acquisition and wireless data transmission, the system can be solely powered by natural fingertip perspiration while detecting glucose, ascorbate, lactate, and levodopa levels over extended periods. The integrated sweat monitoring system on the fingertip provides a solution for effortless, reliable, and self-sustainable comprehensive non-invasive metabolic monitoring.

Lecturer:

Dr. Shichao Ding

Lecturer Bio:

Dr. Shichao Ding is currently a postdoctoral scholar at University of California San Diego and worked with distinguished professor Joseph Wang. He received his Ph.D. degree from Washington State University (PI: Prof. Yuehe Lin) in 2022, respectively. His research focuses on functional nanomaterials-based (especially single-atom catalyst/nanozyme) electrocatalysis and enzyme-like catalysis, biosensing, and wearable electronics/microgrid. He has published 78 papers (34 papers as first/co-first or corresponding authors), including Nature Medicine, Nature Electronics, Nature Review Materials, Nature Review Endocrinology, Advanced Materials, Advanced Energy Materials, etc. His papers have been cited more than >3,300 times with an H index of 31 (Google Scholar). Dr. Ding currently serves as the Editorial board member of Bioengineering, Youth/Junior editors of The Innovation, Advanced Powder Materials, Exploration, VIEW, Soft Science, Med-X, etc, and Peer reviewers for 100 journals, including Nature Synthesis, Nature Communications, etc, for reviewing a total of 400 times.

Lecture Time:

November 16, 1:30 PM

Location:

Classroom JA105, Jiangwan Campus, Fudan University