THURSDAY, May 9, 2024 -- In the short term, bariatric surgery is associated with a greater risk for venous thromboembolism (VTE), but in the long-term, it is associated with lower risk, according to a study published online April 30 in Obesity Surgery.Laura B. Harrington, Ph.D., M.P.H., from Kaiser Permanente Washington Health Research Institute in Seattle, and colleagues evaluated the association between bariatric surgery and long-term VTE risk.

2024年5月9日，星期四——根據(jù)4月30日《肥胖手術(shù)》在線發(fā)布的一項研究，減肥手術(shù)在短期內(nèi)與靜脈血栓栓塞（VTE）風(fēng)險較高有關(guān)，但從長期來看，與較低風(fēng)險相關(guān)。西雅圖凱撒永久華盛頓健康研究所（KaiserPermanenteWashington HealthResearch Institute）的LauraB.Harrington博士及其同事評估了減肥手術(shù)與長期VTE風(fēng)險之間的關(guān)系。

The analysis included 30,171 adults with body mass index?≥35 kg/m2 who underwent bariatric surgery (January 2005 to September 2015) and 218,961 matched nonsurgical patients.The researchers found that at 30 days post-index date, bariatric surgery was associated with a greater VTE risk (adjusted hazard ratio [aHR],?5.01) and greater pulmonary embolism (PE) risk (aHR,?3.93) compared with no bariatric surgery.

這項分析包括30171名成年人的體重指數(shù)?≥接受減肥手術(shù)（2005年1月至2015年9月）的35公斤/平方米患者和218961名匹配的非手術(shù)患者。研究人員發(fā)現(xiàn)，在索引日期后30天，減肥手術(shù)與更大的VTE風(fēng)險相關(guān)（調(diào)整后的危險比[aHR]，?5.01）和更大的肺栓塞（PE）風(fēng)險（aHR，?3.93）與沒有減肥手術(shù)相比。

However, at one year post-index date, bariatric surgery was associated with a lower VTE and PE risk (aHR,?0.52 and 0.30, respectively). Similarly, at five years post-index date, lower VTE and PE risks persisted (aHR,?0.59 and 0.45, respectively).'As patients and their clinicians weigh the risks and benefits of bariatric surgery, our finding provides additional evidence to consider not only the procedure's risks in the short-term, but to balance these with potentially strong long-term benefits,' the authors write.Abstract/Full Text (subscription or payment may be required)Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox..

然而，在索引日期后一年，減肥手術(shù)與較低的VTE和PE風(fēng)險相關(guān)（aHR，?分別為0.52和0.30）。同樣，在指數(shù)發(fā)布五年后，VTE和PE風(fēng)險仍然較低（aHR，?分別為0.59和0.45）作者寫道，隨著患者及其臨床醫(yī)生權(quán)衡減肥手術(shù)的風(fēng)險和益處，我們的發(fā)現(xiàn)提供了額外的證據(jù)，不僅可以考慮手術(shù)在短期內(nèi)的風(fēng)險，還可以平衡這些風(fēng)險與潛在的強大長期益處。摘要/全文（可能需要訂閱或付款）無論您感興趣的主題是什么，都可以訂閱我們的新聞稿，以便在收件箱中獲得Drugs.com的最佳信息。。

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