肥胖是一種慢性代謝性疾病，表現(xiàn)為體重增長(zhǎng)和體內(nèi)脂肪的過(guò)度貯存，這種不平衡的能量代謝紊亂會(huì)造成大腦結(jié)構(gòu)和功能發(fā)生改變，而與認(rèn)知相關(guān)的大腦區(qū)域改變會(huì)增加發(fā)生認(rèn)知障礙的風(fēng)險(xiǎn)。減重代謝手術(shù)（BMS）作為治療肥胖和改善肥胖相關(guān)合并癥的有效手段，術(shù)后腦區(qū)結(jié)構(gòu)與認(rèn)知功能明顯改善。本文綜述了BMS術(shù)后認(rèn)知功能改變的神經(jīng)影像學(xué)基礎(chǔ)和認(rèn)知功能評(píng)估的最新進(jìn)展，討論了BMS術(shù)后腦區(qū)結(jié)構(gòu)改變對(duì)認(rèn)知功能的影響，旨在為進(jìn)一步探索術(shù)后認(rèn)知功能改變機(jī)制研究提供參考。

Obesity is a chronic metabolic disease manifested by weight gain and excessive storage of body fat. This imbalanced energy metabolism disorder causes changes in brain structure and function, while changes in brain regions associated with cognition increase the risk of cognitive impairment. Bariatric metabolic surgery (BMS) is an effective means to treat obesity and improve obesity-related complications, and the structure and cognitive function of brain regions are significantly improved after surgery. This article reviews the latest progress in the neuroimaging basis of cognitive function changes and cognitive function assessment after BMS. It discusses the impact of postoperative brain area structure changes on cognitive function, aiming to provide a reference for further exploring the mechanism of postoperative cognitive function changes.

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