減重代謝手術后神經影像改變與認知功能評估的研究進展
肥胖是一種慢性代謝性疾病,表現(xiàn)為體重增長和體內脂肪的過度貯存,這種不平衡的能量代謝紊亂會造成大腦結構和功能發(fā)生改變,而與認知相關的大腦區(qū)域改變會增加發(fā)生認知障礙的風險。減重代謝手術(BMS)作為治療肥胖和改善肥胖相關合并癥的有效手段,術后腦區(qū)結構與認知功能明顯改善。本文綜述了BMS術后認知功能改變的神經影像學基礎和認知功能評估的最新進展,討論了BMS術后腦區(qū)結構改變對認知功能的影響,旨在為進一步探索術后認知功能改變機制研究提供參考。
Obesity is a chronic metabolic disease manifested by weight gain and excessive storage of body fat. This imbalanced energy metabolism disorder causes changes in brain structure and function, while changes in brain regions associated with cognition increase the risk of cognitive impairment. Bariatric metabolic surgery (BMS) is an effective means to treat obesity and improve obesity-related complications, and the structure and cognitive function of brain regions are significantly improved after surgery. This article reviews the latest progress in the neuroimaging basis of cognitive function changes and cognitive function assessment after BMS. It discusses the impact of postoperative brain area structure changes on cognitive function, aiming to provide a reference for further exploring the mechanism of postoperative cognitive function changes.
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